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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
14.55
Human Site:
T254
Identified Species:
22.86
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
T254
H
P
L
R
S
R
V
T
R
E
L
R
A
A
V
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
T254
H
P
L
R
S
R
V
T
R
E
L
R
T
A
V
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
A367
H
P
L
R
S
R
V
A
R
E
L
R
T
A
V
Dog
Lupus familis
XP_548434
951
104664
A316
H
P
L
R
G
R
V
A
R
E
L
R
T
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
T247
H
S
L
R
S
R
V
T
Q
E
L
W
M
A
M
Rat
Rattus norvegicus
O08874
985
112050
T305
L
S
L
V
A
S
P
T
L
S
P
R
Q
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
S354
H
P
T
R
S
L
V
S
R
E
L
R
E
G
T
Chicken
Gallus gallus
XP_422357
1013
114806
T330
L
S
L
V
S
S
P
T
L
S
P
R
Q
S
V
Frog
Xenopus laevis
Q7ZX15
486
56292
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
I293
T
V
G
S
S
P
G
I
G
L
Q
R
E
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
H110
Q
V
C
T
L
V
V
H
K
K
C
H
L
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
E167
A
M
R
R
K
I
H
E
V
T
G
H
K
F
M
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
C165
L
E
V
R
I
M
G
C
Q
D
L
Q
E
M
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
D242
S
Y
V
T
I
K
I
D
D
T
I
K
A
R
T
Red Bread Mold
Neurospora crassa
P87253
1142
127954
M328
E
H
P
V
P
I
A
M
L
W
V
R
I
S
D
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
93.3
86.6
80
N.A.
66.6
20
N.A.
60
33.3
0
13.3
N.A.
13.3
N.A.
6.6
13.3
P-Site Similarity:
100
93.3
86.6
80
N.A.
80
40
N.A.
66.6
40
0
20
N.A.
33.3
N.A.
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
7
14
0
0
0
0
14
34
0
% A
% Cys:
0
0
7
0
0
0
0
7
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
7
7
0
0
0
0
7
% D
% Glu:
7
7
0
0
0
0
0
7
0
40
0
0
20
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
7
0
7
0
14
0
7
0
7
0
0
7
0
% G
% His:
40
7
0
0
0
0
7
7
0
0
0
14
0
0
0
% H
% Ile:
0
0
0
0
14
14
7
7
0
0
7
0
7
0
7
% I
% Lys:
0
0
0
0
7
7
0
0
7
7
0
7
7
0
0
% K
% Leu:
20
0
47
0
7
7
0
0
20
7
47
0
7
0
7
% L
% Met:
0
7
0
0
0
7
0
7
0
0
0
0
7
7
20
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
34
7
0
7
7
14
0
0
0
14
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
14
0
7
7
14
0
0
% Q
% Arg:
0
0
7
54
0
34
0
0
34
0
0
60
0
14
0
% R
% Ser:
7
20
0
7
47
14
0
7
0
14
0
0
0
27
0
% S
% Thr:
7
0
7
14
0
0
0
34
0
14
0
0
20
0
14
% T
% Val:
0
14
14
20
0
7
47
0
7
0
7
0
0
0
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _